Fludrocortisone (E6062-GRP)

Fludrocortisone (Alflorone, 9α-Fludrocortisone) is a synthetic mineralocorticoid which increases pressor sensitivity to circulating catecholamines and angiotensin, alters intravascular volume, and has central adrenergic effects. It is beneficial in the treatment of hypotensive disorders: orthostatic hypotension, vasodepressor carotid sinus syndrome, and vasodepressor neurocardiogenic syndrome.