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FL-411

FL-411 (S1027-GRP)

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Description

FL-411 (BRD4-IN-1) is a potent and selective inhibitor of Bromodomain-containing protein 4 (BRD4) with IC50 of 0.43 μM for BRD4(1). FL-411 induces ATG5-dependent autophagy-associated cell death (ACD) by blocking BRD4-AMPK interaction.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S1027
Target Autophagy