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Fexagratinib (AZD4547)

Fexagratinib (AZD4547) (S2801-GRP)

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Description

Fexagratinib (AZD4547,ABSK 091) is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM in cell-free assays, weaker activity against FGFR4, VEGFR2(KDR), and little activity observed against IGFR, CDK2, and p38. Phase 2/3.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S2801
Target FGFR