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Fenebrutinib (GDC-0853)

Fenebrutinib (GDC-0853) (S8421-GRP)

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Description

Fenebrutinib (GDC-0853) is a potent, selective, and non-covalent bruton's tyrosine kinase (BTK) inhibitor with an Ki value of 0.91 nM for Btk with >100-fold selectivity over 3 off-targets (Bmx :153-fold, Fgr: 168-fold, Src:131-fold).

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S8421
Target BTK