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Evofosfamide (TH-302)

Evofosfamide (TH-302) (S2757-GRP)

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Description

Evofosfamide (TH-302) is a selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM, demonstrates 270-fold enhanced cytotoxicity under hypoxia versus their potency under aerobic conditions, stable to cytochrome P450 metabolism.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S2757
Target Others