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EPZ004777

EPZ004777 (S7353-GRP)

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Description

EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM in a cell-free assay and demonstrates >1,200-fold selectivity for DOT1L over all other tested PMTs. EPZ004777 induces apoptosis.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S7353
Target Histone Methyltransferase