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Dooku1

Dooku1 (S2953-GRP)

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Description

Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. Dooku1 inhibits 2 μM Yoda1-induced Ca2+-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S2953
Target Mechanosensitive Channel