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Dimethyl itaconate

Dimethyl itaconate (E1281-GRP)

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Description

Dimethyl itaconate can reprogram neurotoxic to neuroprotective primary astrocytes through the regulation of LPS-induced Nod-like receptor protein 3 (NLRP3) inflammasome and nuclear factor 2/heme oxygenase-1 (NRF2/HO-1) pathways.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E1281
Target NLRP3