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Devimistat (CPI-613)

Devimistat (CPI-613) (S2776-GRP)

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Description

Devimistat (CPI-613), a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase in NCI-H460 cell line, disrupts tumor cell mitochondrial metabolism. CPI-613 induces apoptosis in pancreatic cancer cells. Phase 2.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S2776
Target Dehydrogenase