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Depatuxizumab mafodotin

Depatuxizumab mafodotin (D4042-GRP)

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Description

Depatuxizumab Mafodotin (Depatux-M, ABT-414) is an antibody-drug conjugate consisting of an EGFR IGg1 monoclonal antibody conjugated to the tubulin inhibitor monomethyl auristatin F via a stable maleimidocaproyl link. Depatuxizumab Mafodotin is used in the treatment of recurrent EGFR-amplified Glioblastoma (GBM).

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# D4042
Target EGFR