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Dacomitinib hydrate

Dacomitinib hydrate (E4904-GRP)

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Description

Dacomitinib hydrate(PF-00299804, PF-804) is an orally administered, highly selective irreversible inhibitor targeting pan-ERBB receptors, with an IC50 of 6.0 nM for EGFR, 45.7 nM for ERBB2, and 73.7 nM for ERBB4. It also demonstrates anti-tumor activity.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E4904
Target EGFR