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D34-919

D34-919 (E4704-GRP)

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Description

D34-919 is potent inhibitor of the ALDH1A3-PKM2 interaction, and prevents the ALDH1A3-mediated enhancement of PKM2 tetramerization. D34-919 mediated in vitro and in vivo treatment enhances and restores chemoradiotherapy-induced apoptosis and sensitivity in glioblastoma (GBM) cells.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E4704
Target Dehydrogenase