Cyanine3 CPG 1000 (LP5377)

Cyanine3 CPG 1000 is a controlled-pore glass (CPG) with a Cyanine3 dye covalently attached via a linker. The support is intended for the automated solid-phase synthesis of oligonucleotides using the phosphoramidite method. Its use allows for obtaining an oligonucleotide with a fluorescent label at the 3′-end without additional post-synthetic labeling steps. The pore size of 1000 Å is optimal for synthesizing long oligonucleotide chains, up to 120 nucleotides in length. Cyanine3 (Cy3®) is a bright fluorescent dye in the orange-red spectral region with an absorption maximum at 555 nm and an emission maximum around 570 nm. Oligonucleotides synthesized using this reagent can be used in molecular biology methods such as real-time PCR (qPCR), fluorescent in situ hybridization (FISH), FRET, and surface-enhanced Raman spectroscopy (SERS).