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Cu(II)-Elesclomol

Cu(II)-Elesclomol (E4801-GRP)

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Description

Cu(II)-Elesclomol, a Cu2+ complex of Elesclomol, is a weak inhibitor of DNA topoisomerase I. It is also highly capable of inducing cuproptosis and apoptosis. It induces DNA double-strand breaks in K562 cells and causes a G1 cell cycle block. Cu(II)-Elesclomol displays anticancer activity.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E4801
Target Topoisomerase