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Cryptotanshinone (Tanshinone C)

Cryptotanshinone (Tanshinone C) (S2285-GRP)

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Description

Cryptotanshinone (Tanshinone C) is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none against STAT1 nor STAT5. Cryptotanshinone induces ROS-dependent autophagy and mitochondria-mediated apoptosis.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S2285
Target STAT