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CRCD2

CRCD2 (E1406-GRP)

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Description

CRCD2 is an NT5C2 (cytosolic 5’ nucleotidase II) inhibitor with a kd of 70.9 μM. It enhances the cytotoxic effects of 6-MP and effectively reverses thiopurine resistance mediated by genetic and non-genetic mechanisms of NT5C2 activation in ALL.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E1406
Target Others