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Compound 401

Compound 401 (S6506-GRP)

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Description

Compound 401 is a synthetic inhibitor of DNA-PK(IC50=0.28 μM) and mTOR (IC50=5.3 μM). It has no inhibition on p110α/p85α PI3K (>100 μM) and blocks the phosphorylation of S6 kinase 1 Thr389 and Akt Ser473 in COS7 cells.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S6506
Target DNA-PK