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Cobimetinib (GDC-0973)

Cobimetinib (GDC-0973) (S8041-GRP)

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Description

Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, and showing no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Cobimetinib induces apoptosis. Phase 3.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S8041
Target MEK