CMP8 (S3557-GRP)

CMP8 is a selective and potent ligand for the estrogen receptor which binds to the mutant estrogen receptor ligand-binding domain (ERLBD) with IC50 of 29 nM, 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα, and hERβ, respectively.