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CHZ868

CHZ868 (S7899-GRP)

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Description

CHZ868 is an inhibitor of type II JAK2 with an IC50 value of 0.17 μM in EPOR JAK2 WT Ba/F3 cells. CHZ868 demonstrates 60- to 70-fold higher inhibition of JAK1-/TYK2-mediated nuclear STAT1 translocation compared to pan-JAK inhibitors.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S7899
Target JAK