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CGP 57380

CGP 57380 (S7421-GRP)

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Description

CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases. CGP 57380 upregulates β-catenin and potentiates radiation-induced apoptosis.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S7421
Target MNK