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CFT8634

CFT8634 (E1177-GRP)

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Description

CFT8634 is a potent BRD9 degrader with DC50 of 3 nM. It forms a ternary complex with BRD9 and an E3 ligase, resulting in BRD9 ubiquitination. CFT8634 is used in the treatment of SMARCB1-perturbed cancers.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E1177
Target Epigenetic Reader Domain