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CBR-5884

CBR-5884 (S9645-GRP)

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Description

CBR-5884 is a selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and was selectively toxic to cancer cell lines with high serine biosynthetic activity.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S9645
Target Dehydrogenase