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CBR-470-1

CBR-470-1 (E1220-GRP)

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Description

CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E1220
Target Nrf2