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CBL0137 HCl

Selleck

CBL0137 HCl (S8483-GRP)

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Description

CBL0137 (CBLC137, Curaxin 137) HCl activates p53 and inhibits NF-κB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It also inhibits histone chaperone FACT (facilitates chromatin transcription complex).

Specifications

Manufacturer Cat# S8483
Target p53