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Canertinib dihydrochloride

Canertinib dihydrochloride (S0711-GRP)

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Description

Canertinib (CI-1033, PD-183805, compound 18) dihydrochloride is a potent and irreversible inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. Canertinib dihydrochloride inhibits cellular EGFR and ErbB2 autophosphorylation with IC50 of 7.4 nM and 9 nM, respectively.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S0711
Target EGFR