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Brigatinib

Brigatinib (S8229-GRP)

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Description

Brigatinib is a potent and selective ALK (IC50, 0.6 nM) and ROS1 (IC50, 0.9 nM) inhibitor. It also inhibits IGF-1R, FLT3, and mutant variants of FLT3 (D835Y) and EGFR with lower potentcy.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S8229
Target ALK