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Brepocitinib (PF-06700841)

Brepocitinib (PF-06700841) (S8804-GRP)

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Description

Brepocitinib (PF-06700841, PF-841) is a potent inhibitor of Tyk2 and Jak1 with IC50s of 23 nM, 17 nM, 77 nM for Tyk2, Jak1 and Jak2 respectively. It has appropriate in-family selectivity against JAK2 and JAK3.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S8804
Target JAK