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BRD0639

BRD0639 (E1007-GRP)

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Description

BRD0639 is a first-in-class PBM-competitive small molecule inhibitor that disrupts the PRMT5-RIOK1 complex with IC50s of 7.5 μM and 16 μM in permeabilized and living cells, respectively.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E1007
Target PRMT