BMS-986449
BMS-986449 (E6404-GRP)
Products
Description
BMS-986449 is a CELMoD molecular glue and a degrader of IKZF2/IKZF4. It redirects the E3 ubiquitin ligase Cereblon to induce the degradation of Helios and Eos in Treg cells, to enhance antitumor immunity, and shows promise for advanced solid tumor research.
Specifications
| Manufacturer | Selleck Chemicals LLC |
|---|---|
| Manufacturer Cat# | E6404 |