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BMS-986142

BMS-986142 (S8381-GRP)

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Description

BMS-986142 is a potent and highly selective reversible small molecule inhibitor of BTK with an IC50 of 0.5 nM. In a panel of 384 kinases, only five kinases were inhibited by BMS-986142 with less than 100-fold selectivity for BTK (TEC, ITK, BLK, TXK and BMX).

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S8381
Target BTK