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BMS-754807

BMS-754807 (S1124-GRP)

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Description

BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM in cell-free assays, less potent to Met (c-Met), Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 2.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S1124
Target c-Met