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BIX 02189

BIX 02189 (S1531-GRP)

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Description

BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM, also inhibits ERK5 catalytic activity with IC50 of 59 nM in cell-free assays, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S1531
Target MEK