Bifemelane hydrochloride (MCI-2016) (S5985-GRP)

Bifemelane hydrochloride (MCI-2016) is a potent, selective and competitive monoamine oxidase A (MAO-A) inhibitor with Ki of 4.20 μM and a noncompetitive inhibitor of MAO-B with Ki of 46.0 μM. Bifemelane hydrochloride exhibits potent antidepressant activity and can be used for the research of cognitive and emotional disturbances related to cerebrovascular disease.