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BI-2865

BI-2865 (E1474-GRP)

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Description

BI-2865 is a none-covalent pan-KRAS Inhibitor. It binds to WT, G12C, G12D, G12V and G13D mutant KRAS with KDs of 6.9, 4.5, 32, 26, 4.3 nM respectively and inhibits the proliferation of G12C, G12D or G12V mutant KRAS expressing BaF3 ce

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E1474
Target Ras