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Bedaquiline

Bedaquiline (S5623-GRP)

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Description

Bedaquiline (TMC-207, R207910), a diarylquinoline, binds to subunit c of mycobacterial ATP synthase and inhibits its activity. It is highly selective for mycobacterial ATP synthase enzyme compared to homologous eukaryotic enzyme (Selectivity Index >20 000).

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S5623