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BC-1215

BC-1215 (S0322-GRP)

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Description

BC-1215 is an inhibitor of F-box protein 3 (Fbxo3, a ubiquitin E3 ligase component) with IC50 of 0.9 μg/mL and LC50 of 87 μg/ml for IL-1β release. BC-1215 inhibits the Fbxo3-TRAF activation pathway by destabilizing TRAF1-6.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S0322
Target E3 Ligase