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BBI-355

BBI-355 (E1991-GRP)

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Description

BBI-355 is an oral, potent, and selective small molecule inhibitor of CHK1 with an IC50 of 0.3 nM. It demonstrates significant anti-tumor activity as a single agent and in combination with targeted therapies in multiple ecDNA+ oncogene amplified tumor models.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E1991
Target Chk