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BAY 87-2243

BAY 87-2243 (S7309-GRP)

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Description

BAY 87-2243 is a potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor. BAY 87-2243 inhibits mitochondrial complex I activity, thus triggering a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis. BAY 87-2243 exerts antitumor activity. Phase 1.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S7309
Target HIF