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BAY-850

BAY-850 (E1983-GRP)

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Description

BAY-850 is a potent and isoform-selective inhibitor of the ATPase family AAA domain-containing protein 2 (ATAD2) bromodomain, with an IC50 of 166 nM in TR-FRET assays. It induces ATAD2 bromodomain dimerization and effectively blocks its interaction with acetylated histones in vitro.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E1983
Target ATPase