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BAL-0028

BAL-0028 (E1970-GRP)

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Description

BAL-0028 (Compound 3), which belongs to the indazole class is an inhibitor of NLRP3 activation with an IC50 value of 25 nM. BAL-0028 binds tightly to the NACHT domain of NLRP3, with KD values ranging from 104 to 123 nM. BAL-0028 also exhibits anti-inflammatory activity.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E1970
Target NLRP3