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Baclofen hydrochloride

Baclofen hydrochloride (E4920-GRP)

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Description

Baclofen hydrochloride is an agonist of the GABAB receptor that mimics the action of GABA, leading to slow presynaptic inhibition via the GABAB receptor. It improves the function of the ubiquitin-proteasome system (UPS) and enhances cell survival in both in vitro and in vivo models of Huntington's disease (HD).

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E4920
Target GABA Receptor