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AZD8055

AZD8055 (S1555-GRP)

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Description

AZD8055 is a novel ATP-competitive mTOR inhibitor with IC50 of 0.8 nM in MDA-MB-468 cells with excellent selectivity (∼1,000-fold) against PI3K isoforms and ATM/DNA-PK. AZD8055 induces caspase-dependent apoptosis and also induces autophagy. Phase 1.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S1555
Target mTOR