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AZD7545

AZD7545 (S7517-GRP)

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Description

AZD7545 is a potent PDHK inhibitor with IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2, respectively. It failed to inhibit PDHK4 at higher concentrations(>10 nM), AZD7545 stimulates PDHK4 activity.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S7517
Target PDHK