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AZD1080

AZD1080 (S7145-GRP)

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Description

AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively, shows >14-fold selectivity against CDK2, CDK5, CDK1 and Erk2.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S7145
Target GSK-3