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AZ3246

AZ3246 (E5947-GRP)

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Description

AZ3246 is a selective inhibitor of HPK1 with an IC50 value of <3 nM. AZ3246 induces IL-2 secretion in T cells with an EC50 of 90 nM and demonstrates antitumor activity in in vivo models.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E5947
Target MAP4K