Aurovist - 15 nmAurovist - 15 nm
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Aurovist - 15 nm

15 nm gold nanoparticles containing 40 mg gold metal. Supplied dissolved in 0.2 mL phosphate buffered saline (PBS: 20 mM sodium phosphate with 150 mM sodium chloride, pH 7.4), filtered through a 0.22 µm filter.

AuroVist™1 is a novel nanotechnology contrast agent based on gold nanoparticles, the first of its kind to be commercially available. AuroVist™ enables greatly enhanced X-ray imaging of blood vessels, tumors, and other biological systems and organs. AuroVist™-15 nm consists of gold nanoparticles with a core diameter of 15 nm, stabilized with a highly water soluble organic shell. This makes them useable at high concentrations (up to at least 200 mg Au/cc) and well tolerated by animals even at high concentrations (LD50 > 5 g Au/kg). Some of the significant unique features and advantages of AuroVist™-15 nm include:

  • Longer blood residence time than iodine agents (~15 hr blood half-life).
  • High Contrast (>1,000 HU initial blood contrast; 40 mg in a 20g mouse).
  • Does not clear through kidneys (for kidney imaging use AuroVist™-1.9nm, #1102).
  • Low toxicity (LD50> 5 g Au/kg).
  • Can achieve higher contrast than standard iodine agents (Gold absorbs ~3 times more than an equal weight of iodine at 20 and 100 keV).
  • Low osmolality, even at high concentrations.
  • Low viscosity, similar to water; easy to inject with minimal trauma, even into small blood vessels.
  • Can be imaged using standard MicroCT, clinical CT, planar X-ray, or mammography.
  • Enhances radiotherapy dose.2

It is particularly useful for MicroCT animal imaging, such as in vivo vascular casting,3 studies of tumors, stroke, atherosclerosis and other vascular conditions.

*not approved for human use.

Cat# Size Price Qty Buy
1115-40MGAU 40 mg Au
£346.80
1115A-5X40MGAU 5 x 40 mg Au
£1,616.40

Additional Information

Property Value or Rating
Manufacturer Cat# 1115
Manufacturer Nanoprobes, Inc.

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