ATT 647N NHS ester (LP1E920)

ATT 647N NHS ester is an amine-reactive dye for labeling various amine-containing molecules in an aqueous phase without using any organic co-solvent. This product is beneficial for the labeling of peptides and proteins that denature in the presence of organic co-solvents, as well as for proteins with low solubility. ATT 647N is a rhodamine-based far-red fluorophore with strong molar absorption, high fluorescence quantum yield, and excellent thermal and photostability. ATT 647N fluorescence is independent of pH in the range of 2 to 11, which supports its application under diverse experimental conditions. Unlike cyanine dyes, ATT 647N exhibits enhanced resistance to atmospheric ozone degradation, making it highly suitable for microarray and other high-precision applications such as single-molecule detection, super-resolution microscopy techniques (e.g., SIM and STED), flow cytometry (FACS), and fluorescence in situ hybridization (FISH).