ART26.12 (E4780-GRP)

ART26.12 is an inhibitor of fatty acid-binding protein 5 (FABP5) that selectively binds to FABP5 over FABP3, FABP4, and FABP7, exhibiting antinociceptive properties. It alleviates oxaliplatin-induced pain through lipid modulation and cannabinoid receptor activation, with potential for preventing and treating oxaliplatin-induced peripheral neuropathy (OIPN).