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APY29

Selleck

APY29 (S6623-GRP)

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Description

APY29 is a type I kinase inhibitor of IRE1α that binds to the ATP-binding site on IRE1α and inhibits its autophosphorylation (IC50 = 280 nM) and enhances its RNase function (EC50 = 460 nM).

Specifications

Manufacturer Cat# S6623
Target IRE1